As far back as the 16th Century Paracelsus pioneered the view that humans must have certain balances of minerals in their body to maintain health.

400 years later and we are finally catching up... Over the last 50 years Laboratoires Bioligo and CRAO (Centre de Recherches et d'Applications sur les Oligoéléments) have continued the work of several eminent and pioneering French doctors as outlined below:

Timeline of Scientific Discovery...

  • 1895

    Gabriel Bertrand (France) maintains that trace elements are vital for all living cells.

  • 1900's

    Dr J. Sutter (France) student of Brown Sequard, (the father of endocrinology)) establishes a medication based on glandular extracts and ionised trace elements in very small doses. Manganese and Copper were prescribed successfully for arthritis and tuberculosis.

  • 1919

    A report published by Dr Guilly, a surgeon on the battlefields during the First World War, who applied Dr Sutter’s methods of trace element therapy, recorded with photographic proof sensational results on wounds and infections.

  • 1932

    As head of an important private clinic, Dr. Sutter worked with 20 trace element prescriptions which were manufactured under the direction of a first-class French chemist. His medications were registered with Laboratoire Nationale du Controle Pharmaceutique and were readily accepted by doctors and patients alike

  • 1946

    Dr Menetrier, who is regarded as the father of Functional Medicine, progresses the work of Dr. Sutter, establishes that trace elements not only address the symptoms but also strengthen the background condition (diathesis) of the body. He developed the association of different trace elements with different diatheses (terrain/background condition).

  • 1958-1978

    Dr Picard (France) conducted successful clinical trials (50,000 cases) using trace elements to treat osteoarthritis.He proved that for both healing and regeneration of joints to occur, several trace elements need to be taken simultaneously. This was a challenge because of the reactivity of trace elements. Initially, the 12 trace elements were supplied in individual glass ampoules, which was both expensive and awkward for the patients to handle. In 1973 Laboratoires Bioligo successfully combined all the trace elements for Dr Picard’s trials in just two complexes, ensuring that each trace element retained their individually therapeutic action. This pioneering work gave birth to the current range of 17 Global Oligotherapy complexes.

  • 1980

    Michel Deville, Founder and Director of Centre de Recherches et d’Applications sur les Oligo- éléments, Switzerland, creates a simplified system for Dr Picard and progresses the background conditions to include the four diatheses/ background conditions plus an additional diathesis for the endocrine system.

  • 1982

    The CRAO undertake clinical trials and research covering human, plant and animal disorders. They developed the therapy from the classical catalytic trace element therapy to the modern global trace element complexes. The CRAO are regarded as pioneers in the application of catalytic trace elements. All their products are registered with Swissmedic – the Swiss authority governing the manufacture of pharmacological and natural remedies.

Centre de Recherches et d’Applications sur les Oligo- éléments

The CRAO/ Bioligo’s unique history has given them a comprehensive understanding of how to administer natural remedies in the complex landscape of 21st-century health challenges. The Bioligo global trace element complexes fulfil the modern-day challenging requirements of delivering important trace elements in a potent form that is fast-acting, uniquely effective and safe for everybody including children, pregnant or lactating women, the frail and the aged.
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Trace Element Complex for Immunity...

Supporting & strengthening all systems of the body

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